After Dominic D'Agostino graduated from Robert Wood Johnson Medical School with a Ph.D. in Physiology and Neuroscience, he completed two Postdoctoral Fellowships as part of his postgraduate research. The first was a two-year fellowship in Neuroscience, Cell Biology and Physiology at Wright State University Boonshoft School of Medicine. Dominic D'Agostino came to the University of South Florida during his second Postdoctoral Fellowship, which was at USF's department of Molecular Pharmacology and Physiology. He continues to teach advanced courses at the university, and he conducts research in neuroscience, physiology, and nutritional science.
Dominic D'Agostino has written numerous peer-reviewed papers, which have appeared in publications such as the Journal of Microscopy, AJP Regulatory, Integrative and Comparative Physiology, and Microscopy and Microanalysis. Mr. D'Agostino has also contributed chapters to books on topics including physiology and nutritional science. During his career at the University of South Florida , he has developed dietary-related research programs on CNS oxygen toxicity (seizures), epilepsy, cancer, Alzheimer's disease, amyotrophic lateral sclerosis, and other conditions. Groups that have contributed to Dominic D'Agostino's research endeavors include the Office of Naval Research (ONR), the Alzheimer's Association, the Department of Defense (DOD), and the American Heart Association (AHA).
Thoroughly involved in local nonprofit organizations, Dominic D'Agostino has been a Big Brother/mentor in the Big Brothers Big Sisters Association for several years. He supports the Humane Society of Tampa Bay. In addition to spending eight hours per month volunteering at this organization as an animal companion, he is a registered foster parent for animals in need of temporary homes. He works with nonprofit groups that aid homeless people, including Metropolitan Ministries. Dominic D'Agostino also contributes to Lifelink, a group that aims to promote organ donation, by participating in fund-raising events and raising awareness about the organization and its cause.